Clear aligner aims to guide jaw growth and fix underbite without metal braces

NCT ID NCT07703007

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial tests a custom clear aligner designed to correct skeletal Class III malocclusion (underbite) in children aged 8-11 who are still growing. The aligner uses small bite blocks with angled surfaces to gently guide the lower jaw forward during everyday use. Researchers will measure changes in jaw position, tooth alignment, and facial appearance using X-rays taken before and after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a customized functional clear aligner appliance designed as a reverse twin block with 70° inclined planes
What this could lead to
If successful, this approach could offer a more comfortable and aesthetic alternative to traditional braces for correcting underbite in growing children.
What could go wrong
This is a small, early-stage study with only 15 participants, so results may not apply to all cases. The device may not achieve the desired skeletal changes or could cause discomfort.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Dentistry, Mansoura University

    Al Mansurah, Dakahlia Governorate, Egypt

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