Mansoura University

This trial tests whether a gel made from green tea extract (EGCG) can improve the treatment of stage II periodontitis, a moderate form of gum disease. Thirty adults with gum pockets will receive either the gel or a placebo gel, injected into the gums after standard deep cleaning.…

This trial tests whether adding small resin bite turbos to a standard HYRAX expander can speed up upper jaw widening in early adolescents with a narrow upper jaw and crossbite. Half the participants get the expander with bite turbos, and the other half gets the expander alone. Re…

This study tests whether low-dose colchicine, a drug used for gout, can reduce inflammation and symptoms in people with autoimmune or subacute thyroiditis. About 300 adults will be randomly assigned to colchicine, corticosteroids, or supportive care. The goal is to see if colchic…

This study tests whether a mobile app that sends medication reminders can help people with chronic diseases and mild memory problems take their medicines more consistently. Participants use the app on their smartphones to receive alerts and track their doses. The goal is to see i…

This trial tests whether a varnish made from nano-sized eggshell can help reverse the earliest stage of tooth decay (enamel caries) in adolescents aged 15-20. It compares the eggshell varnish against two established treatments: a CPP-ACP paste (GC Tooth Mousse) and a standard 5% …

This study tests whether injecting a mixture of hyaluronic acid and I-PRF (a concentrate of healing factors from your own blood) into the jaw joint, after a cleaning procedure called arthrocentesis, can reduce pain and improve jaw movement in people with a displaced disc. Partici…

This trial tests whether using digital jaw tracking to design full-arch implant-supported dentures leads to better fit and higher patient satisfaction compared to traditional methods. Twenty adults aged 50 to 70 with no upper teeth but with natural lower teeth will be randomly as…

This study tests whether a custom-made PEEK membrane helps grow bone better than a standard PTFE membrane in people needing jawbone rebuilding before dental implants. Thirty adults with missing teeth and insufficient bone in the upper jaw will receive one of the two membranes dur…

This study tests a new, gentler way to clean deep gum pockets in people with advanced periodontitis. It compares a standard deep-cleaning method using larger tools to a minimally invasive approach using thinner, more delicate instruments. The goal is to see if the gentler method …

This study tests whether two diabetes drugs (dapagliflozin and empagliflozin) can help adults with nephrotic syndrome, a kidney condition that causes protein leakage and swelling. About 75 participants will receive either one of these drugs plus standard care, or standard care al…

This study looks at two types of tooth-colored filling materials (ormocer and methacrylate-based bulk-fill) and different polishing methods for cavities near the gum line (class V). About 25 adults with these cavities will receive fillings and be followed for 2 years to see which…

This study tests whether low-intensity shockwave therapy can improve overactive bladder symptoms in women as well as or better than the standard drug solifenacin. Seventy women will be randomly assigned to receive either weekly shockwave sessions for 8 weeks or a daily pill for 1…

This study compares custom-made and ready-made Carriere motion appliances for correcting Class II malocclusion (overbite) in 24 teenagers aged 12-15. The goal is to see which device achieves a proper bite faster and with better patient satisfaction. Participants will be randomly …

This study tests two types of 3D-printed braces to correct underbites in teens aged 11-14. Sixty participants will be split into three groups: one getting a MARA appliance, one getting a fixed twin block, and one getting no treatment. Researchers will measure changes in jaw and t…

This study tests a custom 3D-printed device to widen the upper jaw in 16 young adults aged 18-30. The expander is attached directly to the bone with mini-screws, avoiding pressure on teeth. Researchers will use 3D scans to measure how the jaw bones and teeth move over three month…

This study tests three different methods to rebuild the small triangle of gum tissue between teeth, known as the papilla. The methods are: injecting hyaluronic acid filler, injecting a special blood-based protein (ALB-PRF), or a minor surgical procedure. The trial will enroll 24 …

This study compares three different tooth-colored onlay materials used to repair back teeth with deep cavities that extend below the gum line. Each of the 18 adult participants will receive three onlays made from different materials. Researchers will check the onlays at 2 weeks, …

This study tests whether a nerve block given before mastectomy can prevent depression and chronic pain afterward. Researchers will compare 140 women who receive the block to those who do not. The goal is to see if this simple procedure can improve recovery and quality of life.

This study tests whether specific pelvic floor muscle exercises can reduce or stop the small amount of urine that leaks after men finish urinating, known as post-micturition dribbling. Researchers will compare targeted exercises to general exercises in 120 men aged 18 to 40 over …

This study tests whether a nebulized steroid (budesonide) can prevent stridor—a noisy, difficult breathing caused by airway swelling—after jaw surgery. 62 adults having elective jaw surgery will receive either budesonide or a placebo before surgery. The goal is to see if the ster…

This study looks at whether numbing the upper and lower jaw nerves before surgery can lower pain and the need for extra pain medicine after jaw surgery. About 60 adults having planned jaw surgery will take part. The goal is to see if this nerve block helps control pain better tha…

This study tests whether injecting the painkiller ketorolac into a leg during surgery can reduce pain after the operation. 76 adults having lower leg surgery with a tourniquet will receive either ketorolac or a saltwater solution. The main goal is to see how long pain relief last…

This study compares two medicines—tadalafil (a drug often used for erectile dysfunction) and solifenacin (a standard OAB treatment)—to see which works better for women with overactive bladder. About 480 women in Egypt will take one pill daily for 12 weeks. Researchers will track …

This study tests whether taking a daily low-dose tadalafil plus an on-demand higher-dose sildenafil works better than on-demand sildenafil alone for men with erectile dysfunction who haven't responded to standard treatments. About 500 men will take the combo or a placebo for 12 w…

This study tests three different ways of taking dental impressions to make 3D-printed implant overdentures for people with no teeth. Sixteen participants will try each method for three months, and researchers will measure how well they chew and how satisfied they are. The goal is…

This study tests whether a combination of two drugs (mirabegron and solifenacin) works better than the standard drug (desmopressin) for children who wet the bed. About 120 children will take one of the treatments daily for 3 months. The goal is to see which approach reduces the n…

This study looks at 200 healthy women having a planned C-section under spinal anesthesia. It compares two drugs, norepinephrine and ephedrine, to see which one better keeps the heart pumping blood effectively. Researchers use ultrasound to measure heart function at key times duri…