Mansoura University

This trial tests a new surgical technique that avoids cutting the gum tissue between teeth to repair deep bone defects caused by gum disease. The procedure uses a synthetic bone graft and a special gel to help the bone regenerate. The study includes 60 adults aged 35 to 65 with a…

This trial tests whether applying a gel made from tooth-enamel proteins (enamel matrix derivative) during immediate dental implant placement can improve healing and implant stability. Adults aged 18 to 45 who need a lower molar replaced will receive either the gel or standard imp…

This study compares two dental appliances—a palatal crib and bonded spurs—to treat anterior open bite in children aged 7 to 12. Twenty kids will be randomly assigned to one of the two braces and followed for 6 months. The goal is to see which appliance works better and is more co…

This study compares two types of digitally made telescopic double crown prostheses—rigid and non-rigid—used to replace missing teeth by connecting to natural teeth and implants. Researchers want to see which design leads to healthier soft tissue around the support teeth and highe…

This study compares two ways to prevent heavy bleeding after a planned C-section: one drug (carbetocin) alone versus the same drug plus a slow drip of another (oxytocin). About 332 women having planned C-sections will take part. The goal is to see if the single drug works just as…

This study compares two diabetes medications—imeglimin and metformin—in 176 adults newly diagnosed with type 2 diabetes. Participants will take one of the two drugs for 12 weeks. The main goal is to see which drug better improves mitochondrial function, measured by a blood test c…

This study compares two drugs, milrinone and epinephrine, to treat right heart dysfunction that can occur after cardiac surgery. The trial will enroll 102 adults undergoing heart surgery with a heart-lung machine. The goal is to see which drug better improves right heart function…

This study will compare two laser power settings (high vs low) during a minimally invasive surgery called mini-percutaneous nephrolithotomy for removing kidney stones larger than 20 mm. Seventy adults will be randomly assigned to one of the two laser groups. The main goal is to s…

This study tests whether adding finerenone to standard heart failure treatment (an SGLT2 inhibitor) can reduce deaths and hospitalizations. About 60 adults aged 18-65 with newly diagnosed heart failure will be split into two groups: one gets the standard drug alone, the other get…

This study looks at whether squeezing a handgrip device or walking is better at lowering blood pressure in people with high blood pressure. About 99 adults with stage 1 hypertension will be assigned to one of the two exercises. The goal is to see which activity leads to a greater…

This study will compare two minimally invasive surgeries for kidney stones that are 2-3 cm in size. About 280 adults across nine hospitals will be randomly assigned to either FANS-based flexible ureteroscopy or suction-assisted mini-PCNL. The main goal is to see which method remo…

This study tests a modified surgical technique called periosteal inhibition to see if it helps maintain bone around dental implants placed right after tooth extraction. Thirty adults with a non-restorable back tooth and thin buccal bone will be randomly assigned to get either the…

This study tests whether low-dose atropine eye drops (0.05%) can slow the progression of myopia (nearsightedness) in children. Forty-five kids with worsening myopia will receive one drop of atropine in one eye and a placebo drop in the other eye every night for 24 months. The mai…

This trial compares two ultrasound-guided nerve blocks—retrolaminar block and transverse abdominis plane (TAP) block—to see which one improves recovery and reduces pain after laparoscopic upper abdominal surgery. About 164 adults aged 21 to 65 will receive one of the two blocks b…

This study tests whether virtual reality (VR) can reduce pain, fear, and distress in children aged 6 to 12 during burn dressing changes. Half of the participants will receive standard care plus VR distraction, while the other half receives standard care alone. Pain, fear, and dis…

This study tests whether a structured marital adjustment program can help emotionally divorced wives feel more connected to their husbands. The program includes educational sessions on communication, coping, and problem-solving. Researchers will measure emotional divorce levels b…

This study tests whether Oketani massage, a gentle breast massage technique, helps first-time mothers breastfeed more successfully. Researchers will measure how well babies latch, how comfortable moms feel, and overall breastfeeding confidence. The study involves 100 women who ha…

This study tests whether adding gabapentin to the standard drug solifenacin works better than solifenacin alone for women with overactive bladder. Sixty women will be randomly assigned to one of the two treatments and followed for 3 months. The goal is to see if the combination i…

This study tests whether adding neostigmine to a standard numbing medicine (bupivacaine) in a belly-wall nerve block can improve pain control after cesarean delivery. About 58 women having planned C-sections will receive either the combo or the standard block alone. The goal is t…

This study tests whether applying an ice bag to the groin area after a heart procedure (called PCI) can reduce pain and bruising. Sixty adults who had the procedure through the femoral artery will receive ice therapy for 20 minutes at a time. Researchers will measure pain levels …

This study compares taking tamsulosin every day versus every other day in 288 men aged 40 and older with enlarged prostate and moderate-to-severe urinary symptoms. The goal is to see if the every-other-day schedule controls symptoms just as well while possibly causing fewer sexua…

This study will compare two medicines, phenobarbital and levetiracetam, to see which is safer and more effective at stopping seizures in newborns with moderate to severe brain injury from lack of oxygen (HIE). The trial plans to enroll 66 infants and will measure how many become …

This study tests whether a natural compound called phenolic complex k110-42 can improve attention and thinking in children with Down syndrome. About 108 children aged 4 to 8 will take the compound and have their cognitive skills measured with standard tests. The goal is to ease s…

This study tests whether teaching mothers a 'laid-back' breastfeeding position (leaning back comfortably) improves their breastfeeding experience and comfort compared to the usual cradle hold. Researchers will train 168 pregnant women during their third trimester and follow them …

This study will test whether applying cold packs (cryotherapy) to the perineum can reduce pain from episiotomy stitches in 100 women who had a normal vaginal delivery. Half will receive the cold treatment, and the other half will not. Researchers will measure pain levels to see i…

This study will test whether giving maternity nurses a special training booklet on emergency obstetric care improves how they handle urgent situations. Researchers plan to include 60 nurses working in obstetric departments, emergency operating rooms, and delivery units. The goal …

This study will test whether structured educational sessions can improve how maternity nurses care for patients experiencing abortion. Sixty nurses will attend training covering lectures, demonstrations, and discussions. Researchers will observe their practices before and after t…

This study will compare three ways of making palatal expanders—a device used to widen the upper jaw—in 36 children aged 8 to 13 with crossbite. The methods are fully traditional (using physical molds), hybrid (physical mold plus digital fabrication), and fully digital (using a 3D…

This study tests a special program designed to improve critical thinking, reflective thinking, and motivation to learn in nursing students. About 243 students will take part in the program, which focuses on building skills like problem-solving and open-mindedness. Researchers wil…

This study tests whether smart mind maps—visual tools that combine drawings and keywords—can help nurses in the pediatric intensive care unit (PICU) safely administer high-alert medications (drugs that can cause serious harm if given incorrectly). The researchers will train 70 nu…

This study will give 45 maternity nurses a short empathy and communication training program. Researchers want to see if the training improves how nurses talk to women in labor and whether those women feel more cared for. Nurses and patients will fill out questionnaires before and…