Which surgery is best for 2-3 cm kidney stones? major trial aims to find out

NCT ID NCT07295860

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will compare two minimally invasive surgeries for kidney stones that are 2-3 cm in size. About 280 adults across nine hospitals will be randomly assigned to either FANS-based flexible ureteroscopy or suction-assisted mini-PCNL. The main goal is to see which method removes more stones completely after one month, while also tracking complications, pain, and recovery time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
surgical procedures (FANS-based flexible ureteroscopy and suction-assisted mini-percutaneous nephrolithotomy)
What this could lead to
If successful, this study could help doctors choose the best surgical method for medium-sized kidney stones, leading to fewer complications and better stone clearance.
What could go wrong
This is a surgical comparison trial, not a new drug or device. Results may not apply to all patients, and both procedures carry standard surgical risks like infection or bleeding.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis Urinary Calculi urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ain Shams University

    Cairo, Egypt

  • Alexandria University

    Alexandria, Egypt

  • Assuit University

    Asyut, Egypt

  • Cairo university

    Cairo, Egypt

  • Menoufia University

    Shibīn al Kawm, Egypt

  • Minya University

    Minya, Egypt

  • Tanta University

    Tanta, Egypt

  • Urology and nephrology center

    Al Mansurah, Outside U.S./Canada, 35516, Egypt

  • Zagazig university

    Zagazig, Egypt

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