Can a 'No-Cut' gum surgery regrow lost bone?

NCT ID NCT07737678

Not yet recruiting Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Aug 05, 2026 · Updated 3 times

Summary

This trial tests a new surgical technique that avoids cutting the gum tissue between teeth to repair deep bone defects caused by gum disease. The procedure uses a synthetic bone graft and a special gel to help the bone regenerate. The study includes 60 adults aged 35 to 65 with advanced gum disease and specific types of bone defects. Researchers will measure how much bone fills in and whether gum pocket depth and attachment improve.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a synthetic bone graft (beta-tricalcium phosphate and calcium sulfate) and cross-linked hyaluronic acid, delivered via a minimally invasive surgical technique
What this could lead to: If successful, this approach could offer a less invasive way to regenerate bone lost to gum disease, potentially saving teeth and reducing the need for more extensive surgery.
What could go wrong: This is an early-phase trial with only 60 participants, so results may not apply to everyone. Risks include infection, graft failure, or no improvement in bone fill.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for INTRABONY PERIODONTAL DEFECT are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRABONY PERIODONTAL DEFECT PERIODONTAL DISEASE

More trials for these conditions

Other studies related to the condition(s) this trial covers.