PERIODONTAL DISEASE

This study is testing if adding a special diode laser to a standard deep cleaning procedure helps control gum disease better. Researchers will compare the laser-assisted cleaning to cleaning alone in the same patients. The goal is to see if the laser helps reduce gum pocket depth…

This study is testing whether adding a daily probiotic supplement to a special coenzyme Q10 toothpaste helps improve gum health in pregnant women. Forty participants will receive professional dental cleanings and will use either the toothpaste alone or the toothpaste plus probiot…

This study is testing if adding a lovastatin gel under the gums improves the results of standard deep cleaning for periodontal disease. It will compare the gel to a placebo in 44 adults, including both smokers and non-smokers. Researchers will measure gum health over six months t…

This study is testing whether adding a hydrogen peroxide mouth rinse to standard dental cleaning helps people with moderate to severe gum disease. About 90 participants will use either a 1.5% or 3% strength rinse or a control solution for 12 weeks. Researchers will measure change…

This study is testing whether a spray containing 'good' bacteria (probiotics) can help prevent and control gum disease in older adults. Researchers will compare the probiotic spray to a placebo spray in 90 elderly participants in Hanoi over several weeks. They will check if the s…

This study is testing whether a special oral care routine using lactoferrin (a protein found in milk) in both toothpaste and mouthwash is better than just the toothpaste at preventing gum disease in pregnant women. Forty pregnant women will be randomly assigned to use one of the …

This study aims to understand how genetic immune system problems affect oral health, particularly gum disease. Researchers will compare people with immune disorders, those with severe gum disease, and healthy volunteers by collecting samples like saliva, plaque, and blood. The go…

This study aims to understand if there is a link between how well you sleep and the severity of gum disease (periodontitis). Researchers will examine 48 participants, checking their gum health, having them fill out sleep and fatigue questionnaires, and testing their saliva for ce…

This study aims to see if a protein found in saliva, called Mitofusin-1, is linked to how severe gum disease is and how well treatment works. Researchers will collect saliva and examine the gums of 104 people, including healthy individuals and those with mild to severe gum diseas…

This study aims to understand how gum tissue heals differently in people with severe gum disease, particularly comparing smokers and non-smokers. Researchers will collect small tissue samples during routine gum surgery from 46 participants to analyze healing properties and bacter…

This study aims to understand the link between gum disease, smoking, and specific inflammation markers in saliva. Researchers will compare saliva samples from 116 people with and without gum disease, who are either smokers or non-smokers. The goal is to see if these markers could…