Good bacteria spray could help seniors fight gum disease
NCT ID NCT07258303
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if a probiotic spray containing good bacteria can help prevent and treat gum disease in older adults. Researchers will give 90 elderly participants either the probiotic spray or a placebo for four weeks. They will measure changes in gum health, bleeding, and bad breath to see if the spray is safe and effective.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Patients aged 35 years and older. * Patients diagnosed with periodontal disease based on clinical examination, including gingivitis and periodontitis. * Patients presenting with at least 10 natural teeth in the dental arch. * Patients with stable general health status and able to comply with study procedures. * Patients (or their legal guardians) who provide written informed consent and voluntarily agree to participate in the study. Exclusion Criteria * Patients with unstable general health, acute systemic or oral diseases, or malignant conditions that may interfere with participation. * Patients who are currently receiving treatment for periodontal disease at specialized dental facilities. * Patients currently using any therapeutic or adjunctive products for the management of periodontal disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tuyet Thai Senior Care Center
RECRUITINGHanoi, Hanoi, 100000, Vietnam
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