PERIODONTAL DISEASE

This study tests whether adding coenzyme Q10 toothpaste and daily probiotics to regular dental cleanings can improve gum health in pregnant women. Forty pregnant women between 4-8 months will be split into two groups: one gets the extra supplements, the other doesn't. The study l…

This study tests whether adding a diode laser to standard deep cleaning helps treat gum disease better than cleaning alone. Twenty adults with moderate to severe gum disease will have each side of their mouth randomly assigned to either standard cleaning or cleaning plus laser. T…

This study tests whether a hydrogen peroxide mouth rinse (OROXID®) can improve gum health in people with periodontitis, a serious gum infection. About 90 adults with advanced gum disease will use the rinse alongside standard cleaning. The goal is to see if it reduces pocket depth…

This study compares a new interdental brush with other brushes for adults with gum disease. Over 4 weeks, researchers will measure plaque, gum bleeding, and pocket depth. 88 participants will also rate how easy the brush is to use. The goal is to see which brush works best for da…

This study tests if a probiotic spray containing good bacteria can help prevent and treat gum disease in older adults. Researchers will give 90 elderly participants either the probiotic spray or a placebo for 4 weeks. They will measure changes in gum health, bleeding, and bad bre…

This study tests whether a gel containing lovastatin (a cholesterol drug) placed under the gum can improve standard gum disease treatment. About 44 adults with periodontitis, both smokers and non-smokers, will receive the medicated gel on one tooth and a placebo gel on another af…

This study is testing whether simpler, less invasive methods like taking mouth photos, X-rays, and analyzing spit and plaque samples can accurately detect gum disease. Researchers will compare these methods to the standard full-mouth dental exam. The goal is to find a faster, eas…

This study tests whether using a toothpaste and mouthwash made with lactoferrin can help prevent gum disease in pregnant women. Forty pregnant women in their second trimester will be split into two groups: one using both the toothpaste and mouthwash, and the other using only the …

This study looks at the connection between sleep quality and gum disease (periodontitis) in 48 healthy adults. Researchers will measure participants' sleep patterns, fatigue levels, and certain substances in saliva to see if poor sleep is linked to worse gum health. No treatments…

This study looks at whether a protein called Mitofusin-1 in saliva can help measure the severity of gum disease (periodontitis) and how well treatment works. Researchers will compare levels of this protein in healthy people, those with gum disease, and smokers with gum disease. P…

This study looks at how problems with the immune system can lead to gum disease and other mouth issues. Researchers will collect samples like saliva, plaque, and blood from people with genetic immune defects, healthy people with gum disease, and healthy people without gum disease…

This study aims to find out how often the fungus Candida albicans appears in Syrian adults with gum disease (periodontitis) and how it affects their condition. Researchers will collect samples from 100 patients to detect the fungus and measure gum health. The goal is to better un…

This observational study looks at two types of gum tissue from people with severe periodontitis to understand their role in healing after treatment. Researchers will collect tissue samples during surgery and compare them between smokers and non-smokers. The goal is to learn how t…

This study looks at how gum disease and smoking change certain proteins (inflammasomes) in your saliva. Researchers will compare these proteins in people with healthy gums, those with gum disease, and smokers. The goal is to find a simple saliva test that could help diagnose gum …