Can probiotics and coenzyme Q10 boost gum health during pregnancy?

NCT ID NCT07029360

Recruiting now Disease control Sponsor: University of Pavia Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a daily probiotic tablet and a coenzyme Q10 toothpaste to standard gum cleaning can improve oral health in pregnant women. Forty pregnant women will be split into two groups: one gets the probiotic plus Q10 toothpaste, the other gets only the Q10 toothpaste. Researchers will measure plaque, bleeding, and gum health over six months to see if the combination works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Limosilactobacillus reuteri Prodentis® (probiotic) and coenzyme Q10 toothpaste
What this could lead to: If successful, this could point toward a simple, safe way to improve gum health during pregnancy, potentially reducing risks linked to gum disease.
What could go wrong: This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. The benefits of probiotics and coenzyme Q10 for gum health are not yet proven.

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Conditions

The condition(s) this trial relates to.

coenzyme Q10 deficiency Dental Plaque gingivitis periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COENZYME Q10 DENTAL PLAQUE GINGIVITIS MICROBIOTA PERIODONTAL DISEASE PREGNANCY PROBIOTICS

Contacts and locations

Locations

Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia
RECRUITING

Pavia, Lombardy, 27100, Italy

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