Fish oil and aspirin: a new hope for Smokers' gum health?

NCT ID NCT07673185

Recruiting now Disease control Sponsor: Al-Azhar University Source: ClinicalTrials.gov ↗

First seen Jun 29, 2026 · Last updated Jul 09, 2026 · Updated 3 times

Summary

This study tests whether taking omega-3 fatty acids (fish oil) plus low-dose aspirin can improve gum disease treatment in smokers with advanced periodontitis. Participants receive these supplements or a placebo alongside standard deep-cleaning procedures. The trial measures changes in gum pocket depth, attachment loss, and inflammatory markers over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Omega-3 fatty acids (EPA and DHA) plus low-dose aspirin
What this could lead to: If effective, this combination could offer a simple, low-cost way to boost gum disease treatment in smokers, reducing inflammation and improving outcomes.
What could go wrong: This is a small, early-stage trial with only 40 participants. Results may not apply to all smokers, and the supplements may not provide significant benefit over standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

periodontal disorder periodontitis Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTAL DISEASE PERIODONTITIS (STAGE 3) SMOKING BEHAVIORS

Contacts and locations

Locations

Faculty of Dental Medicine for Girls, Al-Azhar University
RECRUITING

Cairo, 11651, Egypt

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