Fish oil and aspirin: a new hope for Smokers' gum health?

NCT ID NCT07673185

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study tests whether taking omega-3 fatty acids (fish oil) plus low-dose aspirin can improve gum disease treatment in smokers with advanced periodontitis. Participants receive these supplements or a placebo alongside standard deep-cleaning procedures. The trial measures changes in gum pocket depth, attachment loss, and inflammatory markers over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Omega-3 fatty acids (EPA and DHA) plus low-dose aspirin

What this could lead to

If effective, this combination could offer a simple, low-cost way to boost gum disease treatment in smokers, reducing inflammation and improving outcomes.

What could go wrong

This is a small, early-stage trial with only 40 participants. Results may not apply to all smokers, and the supplements may not provide significant benefit over standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

periodontal disorder periodontitis Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Faculty of Dental Medicine for Girls, Al-Azhar University

    RECRUITING

    Cairo, Cairo Governorate, 11651, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••