PERIODONTAL DISEASE
Clinical trials for PERIODONTAL DISEASE explained in plain language.
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App for Moms-to-Be boosts diet and gum health, study finds
Disease control CompletedThis study tested a mobile app called NutriDent4Mom in 264 pregnant women to see if it could improve their nutrition and gum health. The app provided diet and oral care guidance, and was compared to standard care. Results suggest the app may help women eat better and reduce gum i…
Matched conditions: PERIODONTAL DISEASE
Phase: NA • Sponsor: NORKHAFIZAH SADDKI • Aim: Disease control
Last updated May 17, 2026 05:32 UTC
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Gum bone repair: PRF gel vs. enamel matrix – which works better long-term?
Disease control CompletedThis study tested two treatments for deep bone defects caused by gum disease: a gel made from the patient's own blood (PRF) and a tooth-enamel protein gel (EMD). Twenty-eight adults with advanced gum disease received one of the treatments after deep cleaning. Researchers measured…
Matched conditions: PERIODONTAL DISEASE
Phase: PHASE4 • Sponsor: Semmelweis University • Aim: Disease control
Last updated May 11, 2026 20:39 UTC
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New ultrasonic tool for gum disease shows promise in small trial
Disease control CompletedThis study tested a new ultrasonic device for treating gum disease without surgery. Forty adults with chronic periodontitis received either the new device or traditional scaling and root planing. The goal was to see which method better reduced gum pocket depths and improved gum h…
Matched conditions: PERIODONTAL DISEASE
Phase: NA • Sponsor: 251 Hellenic Air Force & VA General Hospital • Aim: Disease control
Last updated May 05, 2026 11:56 UTC
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Laser boosts gum healing for smokers
Symptom relief CompletedThis study tested whether adding a diode laser to standard deep-cleaning treatment helps smokers with severe gum disease. Thirty-three smokers received either standard cleaning alone or cleaning plus laser. After three months, the laser group had shallower gum pockets and lower l…
Matched conditions: PERIODONTAL DISEASE
Phase: NA • Sponsor: Selcuk University • Aim: Symptom relief
Last updated May 17, 2026 05:37 UTC
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Gum disease and diabetes: scientists hunt for hidden clues
Knowledge-focused CompletedThis completed study examined 226 adults aged 30-70 to understand how gum disease (periodontitis) and type 2 diabetes affect each other. Participants were grouped by their blood sugar levels and gum health. Researchers measured immune markers, bacteria, and other substances in bl…
Matched conditions: PERIODONTAL DISEASE
Phase: NA • Sponsor: Sanofi Pasteur, a Sanofi Company • Aim: Knowledge-focused
Last updated May 17, 2026 05:35 UTC
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Gum disease linked to eye inflammation? new study investigates
Knowledge-focused CompletedThis study compared gum health and inflammatory markers in 25 people with non-infectious uveitis (eye inflammation) and 27 healthy individuals. Researchers measured gum pocket depth, bleeding, and levels of inflammatory proteins in saliva, gum fluid, and blood. The goal was to se…
Matched conditions: PERIODONTAL DISEASE
Sponsor: Selcuk University • Aim: Knowledge-focused
Last updated May 17, 2026 05:34 UTC
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Gum inflammation and Alzheimer's: blood clues found in new study
Knowledge-focused CompletedThis study looked at 100 adults over 50 to see if there is a link between gum inflammation and Alzheimer's disease. Researchers measured gum health and checked blood test results. The goal was to understand the connection, not to test a treatment.
Matched conditions: PERIODONTAL DISEASE
Sponsor: Uskudar University • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Blood metal levels may link diabetes and gum disease
Knowledge-focused CompletedThis study looked at levels of three metals—chromium, nickel, and magnesium—in the blood of 74 adults with type 2 diabetes and gum disease. Researchers wanted to see if these metals are connected to how severe the gum disease is. The study did not test any treatment; it only meas…
Matched conditions: PERIODONTAL DISEASE
Sponsor: Kahramanmaras Sutcu Imam University • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Gum fluid test could spot hidden gum disease in denture patients
Knowledge-focused CompletedThis study looked at a protein called pentraxin in the gum fluid of teeth that support fixed dentures. The goal was to find early signs of gum disease that are not visible during a regular checkup. 90 adults who needed fixed dentures and had no visible gum inflammation took part.…
Matched conditions: PERIODONTAL DISEASE
Sponsor: Jagiellonian University • Aim: Knowledge-focused
Last updated May 13, 2026 16:04 UTC
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Spit test could reveal secrets of gum disease
Knowledge-focused CompletedThis study looked at certain proteins in the spit and gum fluid of 44 people—half with gum disease and half healthy. The goal was to see if these proteins could help explain how gum disease works. No treatment was given; it was purely an observation study.
Matched conditions: PERIODONTAL DISEASE
Sponsor: Melis Yilmaz • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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Bad swallowing habits linked to worse gum disease, study finds
Knowledge-focused CompletedThis study looked at 125 adults with gum disease to see how many also have atypical swallowing, where the tongue pushes against teeth abnormally. Researchers checked tongue posture and used questionnaires to find links between swallowing problems and dental issues like loose teet…
Matched conditions: PERIODONTAL DISEASE
Sponsor: University of Roma La Sapienza • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC
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Camera peers inside sinus during dental implant procedure
Knowledge-focused CompletedThis study tested a new dental implant technique in 6 people with low bone in the upper jaw. Surgeons used a special drill and a tiny camera to watch the sinus membrane during the procedure. The goal was to see how often the membrane gets torn and how it stretches, without using …
Matched conditions: PERIODONTAL DISEASE
Phase: NA • Sponsor: Saint-Joseph University • Aim: Knowledge-focused
Last updated May 11, 2026 20:39 UTC
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Smokers' nicotine addiction linked to gum disease ignorance
Knowledge-focused CompletedThis completed study looked at 350 smokers with gum disease (gingivitis or periodontitis) to see if their level of nicotine dependence affects how aware they are of their gum condition. Researchers used a questionnaire to measure nicotine addiction and checked gum health through …
Matched conditions: PERIODONTAL DISEASE
Sponsor: Erzincan University • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC
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Gum disease and osteoporosis: a hidden link in women?
Knowledge-focused CompletedThis study looked at 80 postmenopausal women to see if there is a connection between gum disease and osteoporosis. Researchers measured certain proteins in blood and gum fluid to understand shared causes. The goal was to gather knowledge, not to test a treatment.
Matched conditions: PERIODONTAL DISEASE
Sponsor: Recep Tayyip Erdogan University • Aim: Knowledge-focused
Last updated May 06, 2026 16:02 UTC
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Radiation and mouth viruses: new study links cancer treatment to gum disease
Knowledge-focused CompletedThis study looked at whether radiation therapy for head and neck cancers changes the viruses in the mouth, especially the Epstein-Barr virus (EBV), and how that might affect gum disease. Researchers studied 25 patients receiving radiation and compared them to healthy controls. Th…
Matched conditions: PERIODONTAL DISEASE
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated May 04, 2026 16:20 UTC