Sleep hormone gel boosts gum disease therapy?

NCT ID NCT07605767

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether a melatonin gel applied to the gums can improve the results of standard deep-cleaning treatment for gum disease. Thirty adults with periodontitis received either the melatonin gel or a placebo gel alongside their regular dental cleaning. Researchers measured changes in gum pocket depth and attachment levels after three months to see if melatonin provided extra benefits.

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Conditions

The condition(s) this trial relates to.

periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Liaquat College of Medicine and Dentistry

    Karachi, Sindh, 7290, Pakistan