Light-Activated therapy may boost gum disease treatment, especially for smokers

NCT ID NCT07697963

Completed Disease control Sponsor: University of Pristina Source: ClinicalTrials.gov ↗

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study tests whether adding photodynamic therapy (PDT) to standard deep cleaning (scaling and root planing) improves gum disease treatment more than cleaning alone. The trial includes both smokers and non-smokers to see if the extra treatment helps smokers, who often have worse outcomes. Participants receive both treatments in different parts of their mouth, and the main goal is to measure how much gum pocket depth decreases.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Photodynamic therapy (PDT) plus scaling and root planing
What this could lead to: If PDT proves more effective than standard cleaning alone, it could offer a better way to control gum disease, especially for smokers who often respond poorly to traditional treatment.
What could go wrong: This is a very early-phase study with only 120 participants, so results may not apply broadly. PDT is an add-on treatment and is not expected to cure gum disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTAL DISEASE

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Other studies related to the condition(s) this trial covers.