PERIODONTAL DISEASE

This study tests a new peptide hydrogel for regenerating bone and tissue damaged by severe gum disease. Forty adults will receive either the new hydrogel or a standard hyaluronic acid gel during surgery. Researchers will compare how well each treatment restores gum attachment and…

This study looks at whether a special dental follow-up program (with text message reminders and tips) can help people with type 2 diabetes and gum disease better control their blood sugar. About 516 adults who have already had gum treatment will be split into two groups: one gets…

This study offers free dental check-ups, cleanings, and supplies to pregnant people with gum disease. It compares two noninvasive oral health methods to see which better reduces gum inflammation and improves pregnancy outcomes. About 160 participants under 20 weeks pregnant with …

This study will test a new digital method to measure dental plaque using 3D images from an intraoral scanner. Twenty adults will be scanned before and after plaque is stained, and after brushing. The digital results will be compared with traditional plaque scoring to see if the s…

This study tests whether a simple, low-cost oral health program for pregnant women can reduce the number of babies born too early or too small. About 2,280 pregnant women in rural Nepal will either receive daily antiseptic mouthwash and intensive oral hygiene education, or just a…

This study looks at how common and severe gum disease is in people with rare kidney disorders like Alport syndrome, Fabry disease, and tuberous sclerosis, as well as lupus. Researchers will compare them to people with chronic kidney disease and healthy volunteers. Participants ge…

This study will measure stress and inflammation markers in the blood of 30 adults having gum surgery or a non-surgical gum treatment. Researchers want to see how these markers change during and after the procedure. Participants will give blood samples before, during, and after th…