Could a daily probiotic boost gum health in smokers?

NCT ID NCT07672379

Not yet recruiting Disease control Sponsor: Biruni University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a daily synbiotic supplement (probiotics plus prebiotic) to standard non-surgical gum treatment improves gum health in smokers with advanced periodontitis. 92 smokers and non-smokers will be split into four groups, receiving either the supplement or a placebo for 90 days. Researchers will measure gum pocket depth, attachment levels, and immune and bacterial markers to see if the supplement provides extra benefit.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: synbiotic supplement (probiotics and prebiotic inulin)
What this could lead to: If it works, this could point toward a simple, safe add-on to improve gum treatment outcomes for smokers with periodontitis.
What could go wrong: This is a small, early-stage trial with no phase designation. The supplement may show no added benefit over standard care, and results may not apply to non-smokers or other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTAL DISEASE

Contacts and locations

Locations

Biruni University

Istanbul, Istanbul, 34010, Turkey (Türkiye)

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