Laser and dye combo may boost gum disease treatment

NCT ID NCT07633405

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether adding a light-activated dye (photodynamic therapy) to standard deep cleaning improves gum disease more than cleaning alone. Thirty adults with periodontitis will have one side of their mouth treated with cleaning plus the dye/laser, and the other side with cleaning only. Gum pocket depth and bleeding will be measured after 30 days to see if the extra step helps.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
antimicrobial photodynamic therapy (toluidine blue O dye activated by a 650 nm laser)
What this could lead to
If it works, this could offer a simple, non-invasive way to improve gum health without antibiotics or surgery.
What could go wrong
This is a very small, early-stage trial with only 30 people and a short 30-day follow-up. Results may not last or apply to everyone.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dental School, Catholic University of Santiago de Guayaquil (UCSG)

    Guayaquil, Guayas, 090101, Ecuador

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