Tooth-Enamel gel may boost dental implant healing

NCT ID NCT07727655

Not yet recruiting Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests whether applying a gel made from tooth-enamel proteins (enamel matrix derivative) during immediate dental implant placement can improve healing and implant stability. Adults aged 18 to 45 who need a lower molar replaced will receive either the gel or standard implant placement. Researchers will measure implant stability and bone changes over six months to see if the gel helps the implant fuse with the jawbone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: a gel made from tooth-enamel proteins (enamel matrix derivative, Emdogain)
What this could lead to: If it works, this could lead to a simple way to improve dental implant success and bone healing after tooth extraction.
What could go wrong: This is a small, early-stage trial with only 24 people, so results may not apply to everyone. The gel is generally safe but could cause local swelling or discomfort.

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Conditions

The condition(s) this trial relates to.

Tooth Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TOOTH LOSS

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