Eggshells vs. fluoride: can a kitchen scrap beat standard cavity care?

NCT ID NCT07711132

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This trial tests whether a varnish made from nano-sized eggshell can help reverse the earliest stage of tooth decay (enamel caries) in adolescents aged 15-20. It compares the eggshell varnish against two established treatments: a CPP-ACP paste (GC Tooth Mousse) and a standard 5% sodium fluoride varnish. Over 12 months, the study measures changes in tooth remineralization using a laser device and clinical criteria to see which approach works best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
nano-eggshell varnish, CPP-ACP paste, and sodium fluoride varnish
What this could lead to
If effective, nano-eggshell varnish could offer a natural, low-cost alternative to fluoride for reversing early tooth decay in teens.
What could go wrong
This is a small, early-stage trial with 90 participants, so results may not apply broadly. Nano-eggshell is experimental and may not outperform standard treatments.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Faculty of Dentistry, Mansoura University

    RECRUITING

    Al Mansurah, Egypt