Gum regeneration showdown: which technique wins?

NCT ID NCT07159802

Recruiting now Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests three different methods to rebuild the small triangle of gum tissue between teeth, known as the papilla. The methods are: injecting hyaluronic acid filler, injecting a special blood-based protein (ALB-PRF), or a minor surgical procedure. The trial will enroll 24 adults with mild to moderate gum tissue loss to see which approach works best for restoring volume and improving appearance.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Hyaluronic acid filler, albumin platelet-rich fibrin (ALB-PRF), and a modified surgical technique
What this could lead to: If successful, this could identify the most effective method for restoring lost gum tissue between teeth, improving both appearance and oral health.
What could go wrong: This is a small, early-stage trial with only 24 participants, so results may not apply to everyone. Some treatments may require booster doses or have limited long-term effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PAPILLARY RECONSTRUCTION

Contacts and locations

Locations

Mansoura University
RECRUITING

Al Mansurah, Dakahlia Governorate, 35516, Egypt

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