Jaw joint relief: could a natural protein mix beat standard care?
NCT ID NCT07683650
First seen Jul 06, 2026 · Last updated Jul 15, 2026 · Updated 3 times
Summary
This study tests whether injecting a mixture of hyaluronic acid and I-PRF (a concentrate of healing factors from your own blood) into the jaw joint, after a cleaning procedure called arthrocentesis, can reduce pain and improve jaw movement in people with a displaced disc. Participants are adults aged 18 to 45 with a specific type of jaw joint problem. The trial compares four different treatment approaches to see which works best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- hyaluronic acid and I-PRF (injectable platelet-rich fibrin) mixture
- What this could lead to
- If it works, this could offer a better way to reduce jaw pain and improve mouth opening for people with a common jaw joint problem, possibly reducing the need for more invasive treatments.
- What could go wrong
- This is a small, early-stage trial with only 72 participants, so results may not apply to everyone. The treatment involves a procedure and injection, which carry risks like infection or temporary discomfort.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Faculty of Dentistry Mansoura University
RECRUITINGAl Mansurah, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
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