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Erectile dysfunction drug tested for bladder control in women

NCT ID NCT07416968

Recruiting now Symptom relief Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two medicines—tadalafil (a drug often used for erectile dysfunction) and solifenacin (a standard OAB treatment)—to see which works better for women with overactive bladder. About 480 women in Egypt will take one pill daily for 12 weeks. Researchers will track symptoms like urgency and frequency using bladder diaries and questionnaires.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
tadalafil 5 mg and solifenacin 5 mg
What this could lead to
If tadalafil works better, it could offer women a new, once-daily pill option for overactive bladder with possibly fewer side effects.
What could go wrong
This is a phase 4 trial comparing two existing drugs, so no breakthrough is expected. Tadalafil may not outperform solifenacin, and side effects like headache or upset stomach are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

overactive bladder Urinary Incontinence, Urge

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OVERACTIVE BLADDER (OAB) OVERACTIVE BLADDER SYNDROME

Contacts and locations

Locations

  • Cairo University, faculty of medicine

    RECRUITING

    Cairo, 1211, Egypt

  • Faculty of Medicine - Assiut University

    RECRUITING

    Asyut, Egypt

  • Faculty of Medicine - Banī Suwayf University

    RECRUITING

    Banī Suwayf, Egypt

  • Faculty of Medicine, South Valley University

    RECRUITING

    Qina, Egypt

  • Faculty of medicine, Ain Shams University

    RECRUITING

    Cairo, 1181, Egypt

  • Faculty of medicine, Alexandria University

    RECRUITING

    Alexandria, Egypt

  • Faculty of medicine, Aswan university

    RECRUITING

    Aswān, Egypt

  • Faculty of medicine, Menofia Univeristy

    RECRUITING

    Shibīn al Kawm, Al-Minūfiyyah, Egypt

  • Faculty of medicine, Sohag Univeristy

    RECRUITING

    Sohag, Egypt

  • Faculty of medicine, Tanta University

    RECRUITING

    Tanta, Gharbia Governorate, Egypt

  • Faculty of medicine, Zagazig University

    RECRUITING

    Zagazig, Al-Sharqia, Egypt

  • Faculty of medicine, minia university

    RECRUITING

    Al Minyā, Egypt

  • Urology and Nephrology Center, Mansoura University

    RECRUITING

    Al Mansurah, Dakahlia Governorate, 35516, Egypt

  • faulty of medicine, Tanta Univeristy

    RECRUITING

    Tanta, Gharbia Governorate, Egypt

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