Personalizing bladder treatment: could your other pills determine which drug works best?

This study compares two common medications for overactive bladder (OAB): solifenacin, which blocks nerve signals in the bladder, and mirabegron, which helps the bladder muscle relax. Researchers want to see if a person's 'anticholinergic burden'—the combined effect of other medications that also block those nerve signals—affects how well each drug works. Adults with newly diagnosed OAB who have not yet been treated will take one of the two drugs for two months, and their symptom improvement will be tracked.