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Can a nerve pacemaker that takes breaks still tame an overactive bladder?

NCT ID NCT06170450

Completed Symptom relief Sponsor: University Hospitals Cleveland Medical Center Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests whether a sacral neuromodulation device programmed to cycle on and off (8 hours on, 16 hours off) works as well as continuous stimulation for women with overactive bladder. Participants who have already had a successful trial of the device will be randomly assigned to one of the two settings. The study measures changes in bladder symptoms and quality of life over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
sacral neuromodulation (SNM) device programmed either cyclically (8 hours on, 16 hours off) or continuously
What this could lead to
If cycling works as well as continuous stimulation, patients could enjoy better battery life and less frequent device replacements.
What could go wrong
This is a small, early-stage trial with only 50 participants, so results may not apply to everyone. Cycling might not control symptoms as effectively as continuous stimulation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

overactive bladder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OVERACTIVE BLADDER SYNDROME

Contacts and locations

Locations

  • MetroHealth

    Cleveland, Ohio, 44109, United States

  • University Hospitals

    Cleveland, Ohio, 44106, United States

  • University of Louisville

    Louisville, Kentucky, 40202, United States

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