Common painkiller injected into leg during surgery may extend relief

NCT ID NCT05543785

Recruiting now Symptom relief Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting the painkiller ketorolac into a leg during surgery can reduce pain after the operation. 76 adults having lower leg surgery with a tourniquet will receive either ketorolac or a saltwater solution. The main goal is to see how long pain relief lasts after the spinal anesthesia wears off.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ketorolac (a nonsteroidal anti-inflammatory drug, also known as Toradol)
What this could lead to: If it works, this could provide a simple, safe way to extend pain relief after leg surgery without strong opioids.
What could go wrong: This is a small, early-stage study (76 people) testing a well-known drug in a new way. Results may not apply to all patients or surgeries, and ketorolac can cause side effects like bleeding or stomach irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTOPERATIVE PAIN, ACUTE

Contacts and locations

Locations

Mansoura University Hospitals
RECRUITING

Al Mansurah, Egypt

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