POSTOPERATIVE PAIN, ACUTE

This study tests if a specific nerve block (SPSIP block) can reduce pain after shoulder surgery. About 80 adults having arthroscopic shoulder surgery will receive this block or a placebo. The main goal is to see if it lowers the amount of opioid pain medicine needed in the first …

This study compares two different supportive programs delivered remotely to help women recover after surgery for suspected gynecological cancer. The goal is to see which program works better for reducing pain, anxiety, depression, and sleep problems. About 160 women will take par…

This study tests a new oral painkiller called PF614 for people who have moderate to severe pain after a tummy tuck (abdominoplasty). About 320 adults will take either PF614 or a placebo before surgery and every 12 hours for up to 4 days. Researchers will measure pain levels and h…

This study looks at whether a single dose of meloxicam (a pain reliever) can control pain better than the usual ibuprofen after Mohs surgery for skin cancer. About 300 adults will be split into three groups: one gets a low dose of meloxicam, one gets a higher dose, and one gets s…

This study looks at whether giving the painkiller nalbuphine at different times during knee replacement surgery can better control pain and keep the heart stable in patients aged 65 and older. About 162 participants will receive the same total dose of nalbuphine, but at different…

This study tests if a special numbing injection (nerve block) can reduce pain and the need for strong painkillers after ear surgery in teenagers aged 13 to 18. Half of the 60 participants will get the injection before surgery, and the other half will not. The main goal is to see …

This study compares a long-acting painkiller (liposomal bupivacaine) to a standard one (bupivacaine hydrochloride) for pain relief after lung surgery. About 210 adults having chest surgery will be randomly assigned to one of three groups. The goal is to see if the long-acting ver…

This study aims to find the most effective dose of morphine given into the spinal fluid to control pain after a C-section. Researchers will test different doses in 100 healthy women having planned C-sections, adjusting the dose based on each woman's pain relief. The goal is to ac…

This study tests whether a special nerve block (PENG block) given before hip replacement surgery can help patients have less pain, use fewer strong painkillers, and get out of bed and walk sooner. The study will include 60 adults between 40 and 85 years old who are having hip rep…

This study tests whether giving the painkiller ketorolac directly into the blood flow of a leg (while a tourniquet is inflated) can extend pain relief after lower limb orthopedic surgery. About 76 adults having elective leg surgery under spinal anesthesia will be randomly assigne…

This study compares two types of nerve blocks to prevent chronic pain after video-assisted lung surgery. Forty adults scheduled for elective lung surgery will be randomly assigned to receive either an ultrasound-guided nerve block or a surgeon-given block. The goal is to see whic…