Exercise prescription may improve life after pituitary tumor surgery
NCT ID NCT06163261
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether a tailored physical activity program can improve quality of life and overall health in people who had surgery for a non-functioning pituitary adenoma. Participants will be randomly assigned to receive an individualized exercise plan from a physiotherapist or to continue usual care. The trial will track changes in quality of life, fitness, strength, and fatigue over 12 months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- individualized physical activity and exercise prescription
- What this could lead to
- If it works, this could show that personalized exercise plans improve quality of life and reduce fatigue for people after pituitary tumor surgery.
- What could go wrong
- This is a relatively small trial (120 people) testing a behavioral intervention, so results may not apply to everyone. Exercise adherence and individual differences could affect outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with clinically significant non-functioning pituitary adenoma treated with surgery during the last ten years * Stable hormone replacement therapy ≥ 6 months * Ability to communicate in Swedish. Exclusion Criteria: * Patients with any other pituitary tumors than non-functioning pituitary adenoma * Patients who possibly need tumor intervention, either with surgery or radiotherapy, within one year * Other diseases or co-morbidities that may have significant impact on the outcome variables, including: * Ongoing substance abuse and/or untreated psychiatric disorder, including psychoses and bipolar disease (except treatment with SSRI (Selective Serotonin Reuptake Inhibitor) and or SNRI (Serotonin-Norepinephrine Reuptake Inhibitor) for mild/moderate depression and/or anxiety which is allowed). * Medical therapy with opioids, sedatives or hypnotics (besides treatment with zopiclone and zolpidem which are allowed). * Current or previous history of neurological diseases with impaired mobility. * High alcohol consumption (more than 14 alcohol units per week) * Ongoing treatment for cancer. * Uncontrolled hypertension or presence of clinically significant cardiac disease * Severe respiratory insufficiency. * Severely impaired hepatic function (ALT (Alanine Aminotransferase) and/or AST (Aspartate Aminotransferase) concentrations two times above the upper limit of normal). * Severely impaired renal function (Glomerular filtration rate \<45 ml/min). * Untreated hypo- or hyperthyroidism * Pregnancy or breast feeding.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sahlgrenska Univesity Hospital
RECRUITINGGothenburg, Västra Götaland County, 41345, Sweden
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