One-Dose immunotherapy before surgery shows promise for advanced melanoma

NCT ID NCT07349303

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether one dose of the immunotherapy drug pembrolizumab, given before standard surgery, can shrink or eliminate tumors in people with stage IIb/c melanoma. About 30 adults with thick melanomas that haven't spread to lymph nodes will receive either pembrolizumab or a placebo, then have surgery four weeks later. The main goal is to see how many patients have a significant reduction in tumor cells after just one treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cutaneous melanoma melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sahlgrenska University Hospital

    RECRUITING

    Gothenburg, 41345, Sweden