One shot before surgery: could this immunotherapy shrink aggressive melanomas?

NCT ID NCT07349303

First seen Jan 20, 2026 · Last updated May 08, 2026 · Updated 12 times

Summary

This study tests whether one dose of the immunotherapy drug pembrolizumab, given before standard surgery, can shrink or eliminate tumors in people with stage IIb/c melanoma. About 30 adults with thick melanomas that haven't spread to lymph nodes will receive either pembrolizumab or a placebo, then have surgery four weeks later. The main goal is to see how many patients have a significant reduction in tumor cells after just one treatment.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sahlgrenska University Hospital

    RECRUITING

    Gothenburg, 41345, Sweden

Conditions

Explore the condition pages connected to this study.