Heart pouch closure may cut stroke risk in atrial fibrillation patients

NCT ID NCT06405750

Recruiting now Prevention Sponsor: University Hospital Bispebjerg and Frederiksberg Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether closing a small pouch in the heart (the left atrial appendage) during open-heart surgery can help prevent strokes in people with atrial fibrillation. Researchers will analyze heart tissue, blood, and ECG recordings from 1000 participants to find out who is most at risk for blood clots. The goal is to better identify and protect patients from stroke.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: left atrial appendage closure (a surgical procedure)
What this could lead to: If successful, this could show that routinely closing the heart's auricle during open-heart surgery reduces stroke risk in people with atrial fibrillation.
What could go wrong: This is an observational study, not a randomized trial, so it cannot prove cause and effect. The procedure itself carries surgical risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation stroke disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATRIAL FIBRILLATION STROKE

Contacts and locations

Locations

Rigshospitalet
RECRUITING

Copenhagen, Denmark

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