Stroke recovery breakthrough? scientists hunt for biomarkers to predict HIIT success

NCT ID NCT06059872

Recruiting now Knowledge-focused Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is looking for biological clues to explain why some stroke survivors improve their walking with high-intensity interval training (HIIT) while others do not. Researchers will measure blood lactate, brain chemicals, and blood flow in 55 veterans with chronic stroke. The goal is to build a model that predicts who will respond to HIIT, making rehab more personalized.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: High-Intensity Interval Training (HIIT) cycling sessions
What this could lead to: If successful, this could help doctors predict who will benefit from HIIT after a stroke, personalizing rehabilitation.
What could go wrong: This is a small, early-stage observational study (55 participants) focused on finding predictors, not testing a treatment. The results may not apply to all stroke survivors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LOWER EXTREMITY WEAKNESS, SPASTIC are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Mobility Limitation Paraparesis, Spastic stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOWER EXTREMITY WEAKNESS, SPASTIC STROKE STROKE REHABILITATION WALKING DIFFICULTY

Contacts and locations

Locations

Atlanta VA Medical and Rehab Center, Decatur, GA
RECRUITING

Decatur, Georgia, 30033-4004, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.