Sleep learning may help stroke survivors regain arm movement

NCT ID NCT04312269

Recruiting now Disease control Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether combining a brain-computer interface training with audio cues played during sleep can improve arm function in people who had a stroke at least 6 months ago. 70 participants will practice moving a cursor on a screen using muscle signals, then hear related sounds while they sleep to strengthen memory of the training. The goal is to see if this leads to better real-world arm use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Targeted Memory Reactivation (TMR) during sleep combined with MyoCI training
What this could lead to: If successful, this approach could offer a new way to enhance motor recovery in chronic stroke survivors without drugs or surgery.
What could go wrong: This is an early-stage study with only 70 participants, and the benefits may be small or not generalize to daily life. The intervention is complex and requires consistent sleep monitoring.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STROKE

Contacts and locations

Locations

Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

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