DNA clue may predict stroke risk during common heart procedure in seniors
NCT ID NCT02972008
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is looking at whether a blood test measuring DNA methylation can predict the risk of silent brain injury in elderly patients undergoing TAVR, a minimally invasive heart valve replacement. About 542 people over age 70 with severe aortic stenosis will have their DNA tested before and after the procedure, and brain MRIs will check for new lesions. The goal is to find a biomarker that identifies high-risk patients, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a simple blood test that identifies which elderly patients are at higher risk of brain damage during TAVR valve replacement.
What could go wrong
This is an observational study, not a treatment trial. It only measures risk factors and does not test any intervention to prevent complications.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for STROKE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Hôpital cardiologie, CHRU
RECRUITINGLille, France
Contact