APHASIA
Clinical trials for APHASIA explained in plain language.
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Zapping the brain to help stroke survivors speak again
Symptom relief CompletedThis study tested whether a gentle, non-invasive brain stimulation technique called tDCS could make speech therapy more effective for people with aphasia, a language disorder often caused by stroke. Twenty-three adults who were at least six months past their stroke received speec…
Matched conditions: APHASIA
Phase: NA • Sponsor: Syracuse University • Aim: Symptom relief
Last updated May 17, 2026 02:05 UTC
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Mild electrical stimulation plus speech therapy shows promise for stroke survivors with aphasia
Symptom relief CompletedThis study tested whether mild electrical stimulation (tDCS) combined with speech therapy can help people with long-term language problems after a stroke. 25 adults with aphasia received both treatments and were tested on naming pictures and reading words. The goal was to see if …
Matched conditions: APHASIA
Phase: NA • Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated May 17, 2026 02:03 UTC
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Exercise may boost language after stroke
Symptom relief CompletedThis study looked at whether a high-intensity exercise program is safe and doable for people who have trouble speaking or understanding language after a stroke (aphasia). Twelve stroke survivors took part in either a low-intensity or high-intensity exercise program. Researchers m…
Matched conditions: APHASIA
Phase: NA • Sponsor: University of California, Berkeley • Aim: Symptom relief
Last updated May 17, 2026 02:02 UTC
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Zapping the brain to restore speech after stroke
Symptom relief CompletedThis small pilot study tested whether a gentle electrical current applied to the brain (tACS) could improve word-finding in 11 people with chronic aphasia after a stroke. Participants received either real or fake stimulation while doing language exercises. The goal was to see if …
Matched conditions: APHASIA
Phase: NA • Sponsor: QVITI S.A. • Aim: Symptom relief
Last updated May 17, 2026 02:01 UTC
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Can magnetic pulses help stroke survivors speak again?
Symptom relief CompletedThis study tested whether a non-invasive brain stimulation technique called TMS, combined with language therapy, can improve language function in people with chronic aphasia after a stroke. 86 adults who had a stroke at least 6 months prior participated. They received either real…
Matched conditions: APHASIA
Phase: PHASE2 • Sponsor: H. Branch Coslett • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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App-Based therapy shows promise for Stroke-Related Word-Finding problems
Symptom relief CompletedThis study tested an app called iTALKBetter to help people who have trouble finding words after a stroke. 31 participants used the app to practice naming pictures, and their accuracy was measured before and after therapy. The goal was to see if the app could improve word retrieva…
Matched conditions: APHASIA
Phase: NA • Sponsor: University College, London • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Mimicking speech may unlock words after stroke
Symptom relief CompletedThis study tested a therapy called speech entrainment, where people with non-fluent aphasia (trouble speaking after a stroke) mimic a speaker in real time. 80 participants were split into groups receiving 3, 4.5, or 6 weeks of therapy, or no therapy. The goal was to find the best…
Matched conditions: APHASIA
Phase: PHASE2 • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Brain zaps may help stroke patients speak again
Symptom relief CompletedThis study tested whether a non-invasive brain stimulation technique called HD-tDCS could improve word-finding in 14 people with aphasia (trouble speaking) after a stroke. Participants received stimulation over a language area while practicing naming actions. The goal was to see …
Matched conditions: APHASIA
Phase: NA • Sponsor: Adrian Guggisberg • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Intensive talk therapy boosts communication after stroke
Symptom relief CompletedThis study looked at whether 3 weeks of intensive language therapy can improve everyday communication in people who have had aphasia (trouble speaking or understanding language) for at least 6 months after a stroke. 156 participants received the therapy in a hospital or outpatien…
Matched conditions: APHASIA
Phase: NA • Sponsor: University Hospital Muenster • Aim: Symptom relief
Last updated May 12, 2026 13:42 UTC
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Brain zaps + speech drills show promise for stroke language recovery
Symptom relief CompletedThis study tested whether a gentle brain stimulation technique called tACS, combined with speech training, can improve repetition problems in people who had a stroke and have aphasia (trouble speaking or understanding language). 28 adults received either real or fake stimulation …
Matched conditions: APHASIA
Phase: NA • Sponsor: Ke Dong, MD • Aim: Symptom relief
Last updated May 12, 2026 13:41 UTC
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Can a mild brain zap boost speech therapy for stroke survivors?
Symptom relief CompletedThis pilot study tested whether adding a gentle electrical current to the brain (tDCS) during intensive speech therapy could improve language skills in 10 stroke survivors with non-fluent aphasia. Participants received both real and sham stimulation in random order, with a break …
Matched conditions: APHASIA
Phase: NA • Sponsor: University of Minnesota • Aim: Symptom relief
Last updated May 11, 2026 20:37 UTC
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Paws for words: dog training boosts confidence in stroke survivors
Symptom relief CompletedThis study tested a program where 17 adults with aphasia (a language problem often caused by stroke) learned to train dogs using positive reinforcement. The goal was to see if working with dogs could help them feel more confident, engaged, and improve their quality of life. Parti…
Matched conditions: APHASIA
Phase: NA • Sponsor: Albert Einstein Healthcare Network • Aim: Symptom relief
Last updated May 04, 2026 16:24 UTC
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Tiny trial aims to crack code on who responds to word-finding therapy
Knowledge-focused CompletedThis study tested two different word-finding treatments in 2 people with long-term aphasia (a language disorder often after stroke). The goal was to find out which treatment works best for which person. Participants tried both treatments over several months, and researchers measu…
Matched conditions: APHASIA
Phase: NA • Sponsor: State University of New York at Buffalo • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC
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Can we predict who will benefit from word therapy after stroke?
Knowledge-focused CompletedThis study looked at how often word-retrieval therapy should be given to stroke survivors with aphasia (trouble finding words). Researchers tested 32 Veterans to see which treatment schedule works best and what factors predict improvement. The goal is to personalize therapy for b…
Matched conditions: APHASIA
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Brain wave study reveals gesture connection in aphasia
Knowledge-focused CompletedThis study looked at how the brains of people with aphasia and healthy individuals work together during gestures. Using EEG, researchers measured brain synchronization while participants watched and copied different types of gestures. The goal was to better understand the brain p…
Matched conditions: APHASIA
Sponsor: IRCCS San Camillo, Venezia, Italy • Aim: Knowledge-focused
Last updated May 12, 2026 13:39 UTC