Stroke speech therapy: finding the right dose

NCT ID NCT04364854

Completed Symptom relief Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested speech entrainment therapy (SET) in 80 people with non-fluent aphasia after a stroke. Participants practiced speaking along with an audio-visual computer program for 3, 4.5, or 6 weeks, or received no therapy. The goal was to find the best duration for lasting improvements in spontaneous speech.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Speech entrainment therapy (SET) - a computer program that helps practice fluent speech in real time
What this could lead to: If successful, this could point toward an optimal therapy duration to improve spontaneous speech in people with non-fluent aphasia after stroke.
What could go wrong: This is a small, early-phase study (80 participants) comparing different therapy lengths. Results may not apply to all types of aphasia or stroke survivors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aphasia Aphasia, Broca progressive non-fluent aphasia stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APHASIA APHASIA NON FLUENT STROKE

Contacts and locations

Locations

Medical University of South Carolina

Charleston, South Carolina, 29401, United States
University of South Carolina

Columbia, South Carolina, 29208, United States
University of Utah

Salt Lake City, Utah, 84112, United States

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