Could a common antidepressant help brain function in frontotemporal dementia?
NCT ID NCT06604520
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the antidepressant vortioxetine can improve mood symptoms and thinking abilities in people with early-stage behavioral variant frontotemporal dementia (bvFTD). Participants will take the medication for 12 weeks and undergo brain scans and memory tests before and after treatment. The study aims to see if the drug leads to positive changes in brain activity and symptom relief.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Johns Hopkins Hospital
RECRUITINGBaltimore, Maryland, 21287, United States
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