Can sound waves soothe Dementia's emotional turmoil?
NCT ID NCT07718906
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This early study tests whether a single session of focused ultrasound—using sound waves to gently stimulate a specific brain region—can safely reduce emotional symptoms like agitation, irritability, and anxiety in people with mild dementia. Fifteen participants aged 45 to 80 with Alzheimer's, frontotemporal dementia, or Lewy body dementia will receive the treatment and be monitored for side effects and changes in behavior. The goal is to see if this non-invasive approach is safe enough to study further as a potential alternative to medication.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a single session of focused ultrasound neuromodulation to a target brain region
- What this could lead to
- If safe and effective, this could point toward a non-invasive, drug-free way to manage emotional symptoms like agitation and anxiety in dementia.
- What could go wrong
- This is a very early feasibility study with only 15 participants. It is designed primarily to test safety, not effectiveness, and may not lead to a reliable treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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WVU Rockefeller Neuroscience Institute
Morgantown, West Virginia, 26505, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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