FRONTOTEMPORAL DEMENTIA

This study tests a new gene therapy called AVB-101 for people with a genetic form of frontotemporal dementia (FTD-GRN). The treatment is given once, directly into the brain, to restore a missing protein and potentially slow or stop the disease. About 18 adults aged 30-75 with ear…

This study tests a video-based program called STELLA-FTD for family members caring for a loved one with frontotemporal dementia (FTD). The program helps caregivers manage difficult behaviors and connect with support resources. Researchers will measure changes in caregiver stress …

This study is testing whether a non-invasive brain stimulation technique called tACS can improve symptoms like memory and thinking in people with Alzheimer's disease, Lewy body dementia, frontotemporal dementia, and normal pressure hydrocephalus. About 200 participants will recei…

This study tests whether the antidepressant vortioxetine can improve mood symptoms and thinking skills in people with early-stage behavioral variant frontotemporal dementia (bvFTD). About 50 participants will take the drug for 12 weeks and undergo brain scans and memory tests bef…

This study aims to learn more about neurodegenerative disorders such as ALS, frontotemporal dementia, and progressive supranuclear palsy. Researchers will screen up to 360 adults with these conditions using tests like memory exams, movement assessments, MRI scans, and genetic tes…

This study is looking at whether simple, non-invasive eye scans can help detect and track brain diseases like Alzheimer's, Parkinson's, and multiple sclerosis. Researchers will use special cameras to take detailed pictures of the retina in 2,000 adults—both those with and without…

This study aims to better predict how dementia will progress in individuals with mild cognitive impairment or early dementia. Researchers will collect blood samples and use computer models to track changes in thinking and memory over time. The goal is to improve prognostic confid…