FRONTOTEMPORAL DEMENTIA
Clinical trials for FRONTOTEMPORAL DEMENTIA explained in plain language.
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Brain-Delivered gene therapy tested to halt devastating Early-Onset dementia
Disease control Recruiting nowThis early-phase study is testing a one-time gene therapy called AVB-101 for people with a specific genetic form of frontotemporal dementia (FTD-GRN). The therapy is designed to be delivered directly into the brain to restore a missing protein and potentially slow or stop disease…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Phase: PHASE1, PHASE2 • Sponsor: AviadoBio Ltd • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Brain injection aims to halt devastating dementia
Disease control Recruiting nowThis early-stage study is testing a one-time gene therapy called PBFT02 for adults with specific genetic forms of frontotemporal dementia (FTD). The therapy is delivered via a single injection into the spinal fluid, aiming to deliver a working copy of a missing or faulty gene to …
Matched conditions: FRONTOTEMPORAL DEMENTIA
Phase: PHASE1, PHASE2 • Sponsor: Passage Bio, Inc. • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Brain scan study tests drug for dementia mood symptoms
Symptom relief Recruiting nowThis study is testing if a medication called vortioxetine can help improve mood symptoms like depression and anxiety, as well as thinking skills, in people with early-stage behavioral variant frontotemporal dementia (bvFTD). Researchers will give participants the drug for 12 week…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Apr 01, 2026 14:43 UTC
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Zapping the brain to fight forgetfulness: new hope for dementia patients?
Symptom relief Recruiting nowThis study is testing whether a gentle, non-invasive brain stimulation technique can improve symptoms like memory loss and confusion in people with Alzheimer's disease, Lewy body dementia, and other related conditions. Researchers will compare the effects of real stimulation to a…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Phase: NA • Sponsor: Kuopio University Hospital • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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New virtual program aims to ease the heavy burden on dementia caregivers
Symptom relief Recruiting nowThis study is testing a video-based support program called STELLA-FTD, designed to help family caregivers of people with frontotemporal dementia (FTD). The program connects caregivers in small online groups over 8 weeks to teach skills for managing difficult behaviors and accessi…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Phase: NA • Sponsor: Oregon Health and Science University • Aim: Symptom relief
Last updated Mar 27, 2026 12:41 UTC
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Scientists seek clues to devastating brain diseases in new NIH study
Knowledge-focused Recruiting nowThis study aims to better understand related brain diseases like ALS (Lou Gehrig's disease) and frontotemporal dementia. Researchers are recruiting 360 adults who have been diagnosed with these conditions or carry a genetic risk. Participants undergo detailed testing, including b…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:18 UTC
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Eye scans could spot Alzheimer's years before symptoms
Knowledge-focused Recruiting nowThis study aims to see if detailed pictures of the back of the eye (the retina) can reveal early signs of brain diseases like Alzheimer's and Parkinson's. Researchers will use special, non-invasive camera scans on 2000 people, both with and without these conditions. The goal is t…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC
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Scientists hunt for early warning signs of dementia
Knowledge-focused Recruiting nowThis study aims to create a better prediction model for how memory and thinking problems worsen over time in people with early dementia or mild cognitive impairment. Researchers will collect blood samples, perform brain scans, conduct memory tests, and gather information from clo…
Matched conditions: FRONTOTEMPORAL DEMENTIA
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC