New brain scans aim to spot inflammation in Alzheimer's and Parkinson's

NCT ID NCT04396873

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses special PET scans to measure inflammation in the brains of people with Alzheimer's, Parkinson's, ALS, and other neurodegenerative diseases. Researchers will compare these scans to those from healthy volunteers to see if inflammation levels differ. The goal is to develop better tools for understanding and tracking these diseases.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

11C-MC1, 11C-PS13, and 18F-florbetaben (radioactive tracers injected for PET imaging)

What this could lead to

If successful, this could lead to better ways to detect and monitor brain inflammation in neurodegenerative diseases, aiding diagnosis and treatment development.

What could go wrong

This is an early-phase imaging study, not a treatment trial. It may not find clear differences between patients and healthy volunteers, and results may not directly improve patient care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease amyotrophic lateral sclerosis Cognitive Dysfunction corticobasal syndrome dementia frontotemporal dementia Huntington disease Inflammation Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••