FRONTOTEMPORAL DEMENTIA

This study tested an experimental drug called AL001 in 33 people with frontotemporal dementia caused by specific gene mutations (GRN or C9orf72). The main goals were to check safety and how the drug moves through the body. Researchers also measured changes in certain proteins in …

This study tested a new medicine called TPN-101 in 42 people who have ALS (Lou Gehrig's disease) or frontotemporal dementia caused by a specific gene change (C9orf72). The main goal was to see if the drug is safe and tolerable over 48 weeks. Researchers also looked at how the dru…

This study tested an online tool called WeCareAdvisor that helps caregivers of people with dementia manage difficult behaviors like aggression or wandering. 262 caregivers used the tool to see if it reduced their stress and boosted their confidence. The goal was to make daily car…

This study tested a program called Care Ecosystem, which provides dementia care support over the phone and internet. Over 1,200 people with dementia and their caregivers took part across six health systems. The program aimed to improve quality of life, reduce emergency room visit…

This study tested a video-based support program for 16 family caregivers of people with frontotemporal dementia (FTD). The program aimed to reduce caregiver stress and improve quality of life by teaching coping strategies through videoconference sessions. Results showed that care…

This pilot study tested whether wearable sensors and video recordings can accurately measure apathy in people with frontotemporal dementia compared to healthy volunteers. The goal was to see if technology can capture real-life behaviors like lying down, sitting, and energy use. O…

This study examined 186 people with Alzheimer's, Lewy body, frontotemporal, or corticobasal dementia, plus healthy controls, to see if subtle brain signs (called neurological soft signs) differ between types. Participants had simple movement and coordination tests, along with mem…

This completed study from the University of Pennsylvania interviewed 26 adults—some diagnosed with behavioral variant frontotemporal dementia (bvFTD) and some with a genetic risk—to learn how the condition affects their daily lives, emotions, and sense of self. Researchers aimed …

This study looked at how the front part of the brain helps with reasoning and categorizing things. Researchers compared healthy volunteers to people with frontotemporal dementia or progressive supranuclear palsy. They used tasks, brain scans, and magnetic stimulation to understan…

This study looked at how people with Alzheimer's disease or a type of frontotemporal dementia recall personal memories. Researchers analyzed whether memories were specific events or more general. The goal was to better understand memory loss patterns, not to test a treatment. 39 …

This study examined over 2,200 people with frontotemporal dementia (FTD) or suspected FTD to find out how many cases are linked to specific genes. Researchers collected genetic samples and medical data from participants aged 25 to 85 across multiple countries. The goal was to bet…