Scientists probe frontal Lobe's role in analogical thinking

NCT ID NCT02236832

Completed Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study looked at how the prefrontal cortex helps us understand analogies and categories. Researchers used brain scans, EEG, and magnetic stimulation in 130 healthy volunteers and patients with frontotemporal dementia or progressive supranuclear palsy. The goal was to test ideas about how different parts of the brain handle these thinking tasks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial magnetic stimulation
What this could lead to: If successful, this could improve our understanding of how the brain processes analogies and categories, potentially guiding future therapies for frontal lobe disorders.
What could go wrong: This is a small, early-stage observational and device study, not a treatment trial. Results may not directly lead to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

frontotemporal dementia progressive supranuclear palsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FRONTOTEMPORAL DEMENTIA HEALTHY SUBJECTS PROGRESSIVE SUPRANUCLEAR PALSY

Contacts and locations

Locations

ICM (Institut du cerveau et de la Moelle épinière)

Paris, 75013, France

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