Large study maps genes behind frontotemporal dementia

NCT ID NCT05075187

Completed Knowledge-focused Sponsor: CENTOGENE GmbH Rostock Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study involved over 2,200 people diagnosed with or suspected of having frontotemporal dementia (FTD). Researchers collected blood samples to look for genetic changes linked to the disease. The goal was to find out how common these genetic causes are in people with FTD.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors better understand which genes are linked to frontotemporal dementia, potentially guiding future research and genetic counseling.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly help patients. The results may not apply to all forms of FTD or all populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

frontotemporal dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FRONTOTEMPORAL DEMENTIA

Contacts and locations

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Locations

AGZ of Charite Universitätsmedizin Berlin

Berlin, 12200, Germany
AZ Damiaan

Ostend, West Flanders, 8400, Belgium
Asklepios Klinik Nord - Ochsenzoll

Hamburg, 22419, Germany
Azienda Ospedaliera Universitaria Federico II di Napoli

Naples, 80131, Italy
Azienda Ospedaliero-Universitaria di Parma

Parma, 43126, Italy
Azienda USL-IRCCS of Reggio Emilia

Reggio Emilia, 42121, Italy
Baskent University

Ankara, 06100, Turkey (Türkiye)
Bezmialem Vakif University

Istanbul, 34093, Turkey (Türkiye)
CHU de Liege

Liège, 4000, Belgium
CNS - campus neurológico Torres Vedras

Torres Vedras, 2560-280, Portugal
Clinica Universidad de Navarra

Pamplona, 31008, Spain
Gertrudis Klinik

Leun, Hesse, 35638, Germany
Hacettepe University

Ankara, 06100, Turkey (Türkiye)
Hanau Hospital

Hanau, Hesse, 63450, Germany
Hochtaunus-Kliniken gGmbH

Bad Homburg, 61352, Germany
Hospital Beatriz Ângelo

Loures, 2674-514, Portugal
Hospital Clinico San Carlos

Madrid, 28040, Spain
Hospital Garcia de Orta

Almada, 2805-267, Portugal
Hospital Pedro Hispano

Matosinhos Municipality, 4464-513, Portugal
Hospital Universitari vall D´hebron

Barcelona, 08035, Spain
Hospital Universitario 12 de Octubre

Madrid, 28041, Spain
Hospital da Senhora da Oliveira Guimaraes

Guimarães, 4835-044, Portugal
Istanbul University

Istanbul, 34080, Turkey (Türkiye)
Izmir Economy University Medikalpark Hospital

Izmir, 35575, Turkey (Türkiye)
Koç University Hospital

Istanbul, 34010, Turkey (Türkiye)
Marqués de Valdecilla University Hospital

Santander, 39011, Spain
Mediterraneo Hospital

Athens, 16675, Greece
RWTH Aachen University

Aachen, 52074, Germany
Unidade Psiquiatrica Privada de Coimbra

Coimbra, 3000-606, Portugal
Universitary Hospital La Princesa

Madrid, 28006, Spain
University Hospital Cologne

Cologne, 50937, Germany
University Hospital Dresden

Dresden, Saxony, 01307, Germany
University Hospital Rostock

Rostock, 18057, Germany
University Medical Center Hamburg Eppendorf

Hamburg, Schleswig-Holstein, 20246, Germany
University of Ioannina

Ioannina, 45110, Greece
University of Lübeck

Lübeck, Schleswig-Holstein, 23562, Germany
Università degli studi Gabriele D'Annunzio Chieti-Pescara

Chieti, 66100, Italy