Could a vaccine stop Alzheimer's before it starts? new trial begins
NCT ID NCT07158905
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 1 trial tests an experimental vaccine called AV-1980R that targets tau protein, a key player in Alzheimer's disease. The study enrolls 48 cognitively healthy adults aged 65-80 who have biological signs of early Alzheimer's. Researchers will check if the vaccine is safe and whether it produces antibodies against tau, with the goal of preventing memory loss.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
AV-1980R (tau vaccine)
What this could lead to
If successful, this could lead to a vaccine that prevents Alzheimer's symptoms by targeting tau protein before memory loss begins.
What could go wrong
This is an early Phase 1 safety trial with only 48 people. The vaccine may not trigger a strong immune response or could cause side effects. It is years away from being a proven treatment.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Alzheimer's Research and Treatment Center (Stuart)
RECRUITINGStuart, Florida, 34996, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Alzheimer's Research and Treatment Center (Wellington)
RECRUITINGWellington, Florida, 33414, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Comprehensive Center for Brain Health
NOT_YET_RECRUITINGBoca Raton, Florida, 33433, United States
Contact