LEWY BODY DISEASE

This study is testing a special PET scan (18F-DOPA) to see if it can better detect and measure several conditions, including congenital hyperinsulinism in children, neuroblastoma, neuroendocrine tumors, Parkinson's disease, Lewy body dementia, and brain tumors. About 800 children…

This study is testing a new, non-invasive eye scan that uses different colors of light to look for signs of brain diseases like Alzheimer's, Parkinson's, and dementia. Researchers will scan the eyes of 930 adults aged 30 and older, including those with these conditions and health…

This study looks at how people with Lewy body disease (including Parkinson's and dementia with Lewy bodies) understand sentences. Researchers will compare their language skills to healthy older adults and then test whether a gentle, noninvasive brain stimulation treatment done at…

This pilot study tests whether a non-invasive brain stimulation technique called tDCS can reduce psychotic-like symptoms (like hallucinations and agitation) in people with Lewy Body Dementia. Thirty participants will receive either real or sham stimulation over two weeks. Researc…

This study looks at how the brain, memory, thinking, and movement change over time in people with Lewy body disease, Alzheimer disease, and healthy volunteers. Researchers will use brain scans and brain-wave tests to learn more about these disorders. The goal is to better underst…

This study aims to better understand Lewy body disease, a brain disorder causing thinking and behavior problems that is often hard to diagnose. Researchers will analyze past EEG brain activity recordings from 40 adults to see if the brain's flexibility (how easily it changes stat…

This study is following 2950 people, including healthy individuals and those with memory or movement problems, to learn more about brain diseases like Alzheimer's and Parkinson's. Researchers use advanced brain scans and tests to track changes over time. The goal is to improve di…

This study uses two types of eye imaging (OCT-A and adaptive optics) to look for changes in the retina that might be linked to memory problems, including Alzheimer's and other dementias. Researchers will compare 450 people with and without memory complaints to see if these scans …

This study follows 650 people with early Parkinson's disease or a sleep disorder called iRBD to track how the disease progresses over time. Researchers use brain scans, heart tests, and spinal fluid samples to find markers that predict changes in movement, thinking, and daily lif…

This study aims to help family doctors better detect early signs of Alzheimer's and other dementias. Researchers will test 1,200 adults with memory or thinking problems using simple blood tests and brain scans. The goal is to make accurate diagnosis easier and faster in primary c…

This study is testing whether new blood tests can accurately diagnose the cause of memory problems, potentially replacing the need for more invasive spinal fluid tests. Researchers will compare blood test results with spinal fluid results in 1,200 people being evaluated at a memo…