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Light therapy tested to reverse radiation damage in head and neck cancer patients

NCT ID NCT06708754

Recruiting now Symptom relief Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special light therapy called photobiomodulation (PBM) can reduce swelling and tissue hardening caused by radiation treatment in head and neck cancer survivors. Sixty participants who completed radiation at least 3 months ago will be randomly assigned to receive either real PBM or a sham device. Researchers will measure changes in soft tissue thickness using ultrasound to see if the light therapy helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Photobiomodulation (PBM) therapy using a light-emitting diode (LED) device
What this could lead to
If it works, this could point toward a non-invasive way to ease chronic swelling and stiffness after radiation for head and neck cancer.
What could go wrong
This is a small early feasibility study, not a large definitive trial. The sham control means some participants may not benefit, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms Radiation Fibrosis Syndrome radiation pneumonitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEAD AND NECK CANCER RADIATION FIBROSIS RADIATION LYMPHEDEMA

Contacts and locations

Locations

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

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