Can CBD calm PTSD? new trial seeks answers

NCT ID NCT04550377

Recruiting now Symptom relief Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether cannabidiol (CBD), a compound from cannabis, can reduce PTSD symptoms and improve thinking problems in people with PTSD, including those who also have a mild traumatic brain injury. 120 participants will receive either a low or high dose of CBD or a placebo daily for 8 weeks. The main goal is to see if CBD lowers PTSD severity scores.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cannabidiol (CBD)
What this could lead to: If it works, this could point toward a new treatment option for PTSD symptoms, especially for those who also have a mild traumatic brain injury.
What could go wrong: This is an early Phase 2 trial with only 120 participants, so results may not apply to everyone. CBD may not outperform placebo, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic post-traumatic stress disorder traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-TRAUMATIC STRESS DISORDER TRAUMATIC BRAIN INJURY

Contacts and locations

Locations

New York University School of Medicine
RECRUITING

New York, New York, 10016, United States

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