Double nerve block may cut opioid use after knee surgery

NCT ID NCT06952556

First seen Mar 13, 2026 · Last updated Jun 22, 2026 · Updated 20 times

Summary

This study tests whether adding an extra nerve block (IPACK) to a standard one (adductor canal block) can better control pain and reduce opioid use after knee realignment surgery. About 100 adults undergoing specific knee osteotomies will be randomly assigned to receive either the standard block alone or the standard block plus the IPACK block. The main goal is to measure how much opioid pain medication they need in the first 24 hours after surgery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Bupivacaine

What this could lead to

If successful, this could lead to a standard pain management approach that reduces opioid use after knee osteotomy surgery.

What could go wrong

This is a small, single-center study. The added block may not provide significant extra pain relief, and there is always a risk of side effects from the nerve blocks.

Conditions

The condition(s) this trial relates to.

agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.