Home heart monitoring could stop deadly fetal heart block in its tracks

NCT ID NCT04474223

Recruiting now Disease control Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether pregnant women at high risk for fetal heart block can use a home monitor to catch early signs of the condition. If detected, they receive steroids and IVIG to try to reverse the block before it becomes permanent. The goal is to prevent stillbirth and the need for a lifelong pacemaker.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dexamethasone and IVIG
What this could lead to: If successful, this could provide a way to detect and reverse early fetal heart block, preventing permanent damage and reducing deaths.
What could go wrong: This is an early-stage trial with a small number of participants. The treatments (steroids and IVIG) have risks, and it's not yet known if they will work or if home monitoring is reliable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrioventricular block congenital heart block prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AVB - ATRIOVENTRICULAR BLOCK FETAL AVB

Contacts and locations

Locations

Baylor College of Medicine
RECRUITING

Houston, Texas, 77030, United States
Children's Hospital of Minnesota
RECRUITING

Minneapolis, Minnesota, 55404, United States
Children's National Medical Center/George Washington University
RECRUITING

Washington D.C., District of Columbia, 20010, United States
Cleveland Clinic Lerner College of Medicine
RECRUITING

Cleveland, Ohio, 44195, United States
Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States
Eastern Virginia Medical School (EVMS)
RECRUITING

Norfolk, Virginia, 23507, United States
Mount Sinai
RECRUITING

New York, New York, 10029, United States
NYU Langone Health
RECRUITING

New York, New York, 10016, United States
Perinatal Associates of New Mexico
RECRUITING

Rio Rancho, New Mexico, 87124, United States
Phoenix Children's Hospital/Dignity Health
RECRUITING

Phoenix, Arizona, 85016, United States
Seattle Children's Hospital
NOT_YET_RECRUITING

Seattle, Washington, 98105, United States
Stanford University
RECRUITING

Palo Alto, California, 94305, United States
Stollery Children's Hospital
NOT_YET_RECRUITING

Edmonton, Alberta, AB T6G 2B7, Canada
UH Rainbow Babies / Children's Hospital
RECRUITING

Cleveland, Ohio, 44106, United States
University of California - Los Angeles (UCLA)
RECRUITING

Los Angeles, California, 90095, United States
University of California-San Francisco
RECRUITING

San Francisco, California, 94143, United States
University of Colorado, Denver (UCD)
RECRUITING

Aurora, Colorado, 80204, United States
University of Kentucky / Kentucky Children's Hospital
RECRUITING

Lexington, Kentucky, 40536, United States
University of Louisville / Norton Children's Hospital
NOT_YET_RECRUITING

Louisville, Kentucky, 40202, United States
University of Michigan / C. S. Mott Children's Hospital
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Utah Health
RECRUITING

Salt Lake City, Utah, 84102, United States
University of Vermont Children's Hospital
RECRUITING

Burlington, Vermont, 05401, United States
Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States
Yale University School of Medicine
RECRUITING

New Haven, Connecticut, 06510, United States