New study uses PET scans to see how kidney cancer drug changes key protein
NCT ID NCT07179770
First seen Jun 26, 2026 · Last updated Jul 31, 2026 · Updated 3 times
Summary
This early-phase study is looking at how the drug belzutifan affects a protein called CAIX in people with advanced clear cell kidney cancer. Researchers will use a special PET scan before and after four weeks of belzutifan treatment to measure changes in CAIX levels. The goal is to gather information that could help design better combination treatments in the future. The study involves 12 participants and is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- belzutifan (Welireg) and 89Zr-DFO-girentuximab (TLX250-CDx)
- What this could lead to
- If successful, this study could show how belzutifan affects CAIX levels, paving the way for more effective combination therapies for advanced kidney cancer.
- What could go wrong
- This is a very small, early-phase study with only 12 participants, so results may not apply broadly. The imaging technique is experimental, and the main goal is to gather information, not to test a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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