Nyu Langone Health

This study tested a new way to help people with high blood pressure take their medication regularly. Researchers worked with 10 primary care clinics and over 1,700 patients, using a team of doctors, nurses, and medical assistants supported by electronic health records. The goal w…

This study tested a program where HIV nurses were trained to also manage high blood pressure in people living with HIV. The goal was to see if this approach could lower blood pressure over 12 months. The study involved 830 adults at 30 primary health centers in Lagos, Nigeria.

This study tested whether personalized dietary advice helps people with early-stage type 2 diabetes control their blood sugar better than standard advice or usual care. About 255 participants were split into three groups: personalized diet, standardized diet, or usual care. Resea…

This study looked at whether giving extra help to clinics (called practice facilitation) improves how well they follow a program to help patients take their blood pressure medicine. The study included 652 Latino adults with uncontrolled high blood pressure who were not taking the…

This study tested two methods to help people living with HIV/AIDS in South Africa reduce their cigarette smoking: using e-cigarettes or nicotine replacement therapy (like patches), plus supportive text messages. 106 adults who smoked daily took part. The goal was to see if these …

This pilot study tested whether a butyrate supplement, a type of short-chain fatty acid, could change the gut microbiome and immune responses in people with rheumatoid arthritis who didn't respond well to methotrexate. Twenty participants took the supplement for up to two months.…

This study tested whether a smartphone-based lottery incentive program could help people with high blood pressure take their medication more regularly. Over 400 participants with poorly controlled blood pressure were randomly assigned to receive the lottery program or usual care …

This study tested whether using portable air cleaners at home can improve blood sugar control and reduce inflammation in adults with prediabetes. 150 participants used either real or sham air cleaners for 4 weeks. Researchers measured changes in blood sugar patterns and inflammat…

This study tested a new way to deliver total body radiation to adults with blood cancers who need a stem cell transplant. The goal was to see if this method could effectively target cancer while protecting the lungs. 36 patients took part, and the study focused on safety and how …

This study tested whether using a patient's own bone marrow stem cells (BMAC) mixed with donor bone works as well as the standard bone graft taken from the hip for spinal fusion surgery. Seventeen adults with degenerative disc disease were randomly assigned to one of the two meth…

This phase 2 trial tested whether a gel containing fibroblast growth factor-2 (FGF-2) can close long-standing holes in the ear drum. 52 adults with dry ear drum perforations lasting at least 6 months were randomly assigned to receive either the FGF-2 gel or a placebo, applied up …

This early-stage trial tested a vaccine called UB-312 in 8 people with Parkinson's disease or multiple system atrophy. The vaccine is designed to train the immune system to attack abnormal clumps of a protein called alpha-synuclein, which are linked to these brain disorders. The …

This study tested a drug called daratumumab in 8 people with a specific genetic mutation (STK11/LKB1) in advanced non-small cell lung cancer who had already tried other treatments. The goal was to see if the drug could shrink tumors. The study was small and designed to find early…

This study tested whether adding vancomycin powder and a diluted povidone iodine wash during joint replacement surgery could prevent infections in high-risk patients. Over 2,100 adults with osteoarthritis who were at higher risk due to factors like obesity or smoking took part. T…

This study tested whether a special drape called RADPAD can reduce radiation exposure for doctors performing heart catheterizations. Researchers measured radiation levels for doctors with and without the drape during 1,000 procedures. The goal is to see if this simple shield can …

This study tested a program to help South Asian adults with uncontrolled diabetes. It combined group health coaching sessions led by community health workers with electronic alerts for doctors. Over 850 participants took part. The goal was to see if this approach could lead to a …

This study tested a program where Black and Hispanic young adults (ages 18-29) with HIV used video calls to talk with trained peer health coaches. The goal was to help them take their HIV medication regularly and lower the amount of virus in their blood. The program included eigh…

This study tested a swallowable capsule called HemoPill acute that uses a sensor to detect blood in the upper digestive tract. Researchers compared its readings to standard endoscopy in 15 adults suspected of having upper GI bleeding. The goal was to see if the pill could help do…

This study tested whether sending text message reminders to parents could increase routine vaccination rates in children aged 0-2 years. Over 1,000 families in Brooklyn, New York, whose children were behind on vaccines received texts when shots were due or coming due. The goal wa…

This phase II trial tested whether giving high doses of cyclophosphamide and bortezomib after a stem cell transplant could prevent graft-versus-host disease (GVHD), a serious complication where donor cells attack the patient's body. Twenty-three adults with blood cancers received…

This study tested a program to prevent type 2 diabetes in Chinese immigrants with prediabetes. Participants received weekly videos on diabetes prevention and fresh, culturally appropriate produce. The goal was to see if this approach could help people lose weight and build health…

This study tested a digital toolkit called mSELY that helps teens and parents screen for common mental health problems like anxiety, depression, and conduct issues. Over 560 families in Kenya used the app to learn about mental health and connect with resources. The goal was to se…

This study tested whether automated messages from doctors could keep people with prediabetes engaged in a digital diabetes prevention program. Over 550 participants used the Noom app along with a fitness tracker and scale, and some received tailored text or MyChart messages based…

This study trained community health workers to screen Black men for early signs of high blood pressure. Participants received lifestyle advice and were connected to doctors and social services. The goal was to prevent hypertension from getting worse.

This study tested a program where community health workers led group sessions to help South Asian adults with pre-diabetes lose weight. Nearly 1,000 participants took part. The goal was to see if this approach could help them lose at least 5% of their body weight and reduce their…

This study tested whether adding levetiracetam (a seizure medication) to standard antipsychotics helps people with early psychosis who still have symptoms. 65 participants took either the drug or a placebo for 12 weeks. The goal was to see if it reduces psychotic symptoms and pro…

This study looked at whether different intensities of exercise can reduce anxiety in adults with anxiety disorders. 110 sedentary adults with high anxiety sensitivity were assigned to either low-intensity exercise or a program that gradually increased to high-intensity exercise o…

This study tested whether an 8-week telephone stress management program could reduce stress in women who had a heart attack. 153 women with high stress levels were randomly assigned to either the stress management program or enhanced usual care. The program used mindfulness and c…

This study tested whether doing strength exercises with the healthy leg right after knee surgery can prevent muscle loss in the leg that's in a cast or brace. Fifty patients having meniscus repair or transplant were randomly assigned to either standard rehab or added leg presses …

This study looked at 80 adults with a broken upper arm bone (humeral shaft fracture) to see which initial ER treatment is more comfortable: a pre-made fracture brace or a traditional splint. Over two weeks, researchers tracked pain levels, painkiller use, and skin problems. The g…

This study tested whether a virtual rehabilitation platform called STABL works as well as in-person physical therapy for people recovering from knee surgery (meniscectomy or synovectomy). STABL uses computer vision to guide patients through exercises at home and sends data to the…

This study looked at whether limiting eating to a 6- or 10-hour window each day helps adults who recently lost weight keep it off. 29 participants were randomly assigned to one of two time-restricted eating plans for 12 weeks. The goal was to see if this approach is practical and…

This study tested whether cannabidiol (CBD), a compound from the cannabis plant, can reduce symptoms of social anxiety disorder. Sixty adults with moderate to severe social anxiety took either a high dose of CBD, a lower dose, or a placebo pill twice daily for three weeks. Resear…

This small pilot study tested a cognitive behavioral program to help reduce fatigue in people with chronic kidney disease. Five adults with moderate-to-severe kidney disease took part in remote sessions. The goal was to see if the program was acceptable and to gather data for a l…

This study looked at whether a program called Family Connectors can help family members who care for young adults with psychosis. The program connects caregivers with peers for support and education. Researchers measured changes in social support, caregiver strain, and self-confi…

This study tests a mobile health app called OurChild, designed to help Chinese American families in Brooklyn connect with early childhood mental health resources. The app provides information and tools to support parents of children aged 2 to 6 years old. Researchers will measure…

This completed study followed 316 people with idiopathic generalized epilepsy, including those newly diagnosed and those already known to respond or not respond to treatment. Researchers collected data from seizure diaries, fitness trackers, quality-of-life surveys, and cognitive…

This study tested whether a computer model could find the best combination of active electrodes in a cochlear implant to improve speech understanding. Fourteen adults with cochlear implants tried different settings, including ones recommended by the model, and their speech recogn…

This study looked at 30 healthy older adults to see if changes in a small brain area called the locus coeruleus could be an early sign of Alzheimer's disease. Researchers used brain scans, sleep tests, and spinal fluid analysis to measure brain function, sleep quality, and attent…

This completed study involved 458 pre-K students and their families from 81 high-poverty NYC schools. Researchers tested whether a program called ParentCorps, combined with teacher training, could improve children's emotional well-being and social skills. Parents and teachers rep…

This study tested a computer alert that pops up in doctors' electronic health records to remind them to prescribe recommended heart failure medications. Over 1,100 patients with a specific type of heart failure (reduced ejection fraction) took part across four health systems. The…

This completed pilot study tested a 3D-printed ingestible pill designed to trap bacteria from the gut, including the hard-to-reach small intestine. Ten healthy adults swallowed the pill, which passes naturally through the body. Researchers checked safety and how well the pill cap…

This study compared two brands of thin tubes (sheaths) used during heart procedures to see which doctors liked better. Over 550 patients took part, and doctors rated each sheath on ease of use and performance. The goal was to find out if one sheath was preferred over the other.

This study tested whether an automated system built into electronic health records could improve how pharmacists label and dispense liquid medicines for children. The goal was to reduce parent dosing errors by encouraging metric-only (mL) labels and providing the right dosing too…

This study looked at the genes of 2,500 people who had weight loss surgery (bariatric surgery). The goal was to find out if certain genes are linked to how well the surgery works and if those genes are more common in some ethnic groups. No new treatment was tested; instead, resea…

This study looked at how body weight changes the way aspirin triggers special molecules that help calm inflammation. Researchers gave 103 adults aged 40-70 either aspirin or a placebo and measured these molecules in their blood. The goal was to understand if weight affects aspiri…

This study looked at whether exercise helps adults with high anxiety and anxiety disorders (like generalized anxiety, panic, or social anxiety) better learn to unlearn fear. 54 participants either exercised or sat quietly after a fear-extinction task. Researchers measured skin sw…

This study used brain scans (fMRI) to see how the brain adapts to a new face after a face transplant. Four people with severe facial injuries were scanned before and after surgery to track how their brain learned to recognize the new face as their own. The goal was to understand …

This study used 30 epilepsy patients who already had electrodes implanted in their brains for surgery planning. Researchers applied a mild electrical stimulation called tDCS and measured exactly how the current spread. The goal was to improve computer models that predict where th…

This study followed 544 older couples (ages 65+) over three years to see how dementia affects their relationship and well-being. Both partners answered surveys every six months about their mental health, physical health, and caregiving experiences. The goal was to learn how being…

This study tested a device called Napoleon to help gastroenterology fellows measure colon polyps more accurately during colonoscopies. 46 patients aged 45 and older participated. The goal was to see if using the device improves measurement accuracy compared to just looking, which…

This study created and tested a mobile health program for family caregivers of people with dementia who are at risk for delirium—a sudden, serious confusion. Researchers worked with 8 caregivers to design the program, then tested it with 33 caregivers to see if it was easy to use…

This study tested whether crutches that give feedback to patients help them follow doctor's orders about how much weight to put on their healing leg. Twenty people with certain types of leg fractures used either regular crutches or smart crutches that tracked their weight-bearing…

This study tested a computer tool that helps nurses decide when antibiotics are needed for common respiratory infections like colds and sore throats. The tool, built into the electronic health record, calculates a patient's risk and suggests appropriate care. Researchers measured…

This study tested whether sending text message reminders helps more people complete a take-home colon cancer screening test (FIT) compared to standard phone call reminders. Over 1,200 adults from NYU family health centers took part. Researchers tracked how many completed the test…

This large observational study followed over 15,000 adults in the U.S. to learn more about long COVID (Post-Acute Sequelae of SARS-CoV-2 infection). Researchers tracked symptoms, health history, and biological samples over time in both infected and uninfected people. The goal is …

This study tested whether a gentle electrical stimulation on the ear (taVNS) changes how the pupil reacts and how quickly people learn a simple task. Twelve healthy adults completed computer-based tasks while their pupil size and brain activity were recorded. The goal was to unde…

This study looked at whether giving patients online educational modules before starting voice therapy helps them stay engaged and attend more sessions. Researchers enrolled 42 adults with voice problems (dysphonia) who were recommended for voice therapy. The goal was to see if th…

This completed study examined why people with rheumatoid arthritis (RA) and lupus have a higher risk of heart attacks. Researchers collected blood samples from 176 participants and tested how statins and adenosine A2A receptor agonists affected cholesterol balance in cells. The g…

This study tested a coaching and training program for addiction clinics to help them better treat opioid use disorder. The program included training on tracking patient progress, using medications for opioid use disorder, and improving patient retention. Researchers worked with n…

This completed observational study looked at whether poor sleep quality, specifically slow wave sleep, is linked to brain changes that raise Alzheimer's risk, and whether this link differs between African-American and white older adults. Researchers recruited 210 cognitively norm…