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Stem cells from bone marrow may replace traditional bone graft in spine surgery

NCT ID NCT02297256

Completed Disease control Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether using a patient's own bone marrow stem cells (BMAC) mixed with donor bone works as well as the standard bone graft taken from the hip for spinal fusion surgery. Seventeen adults with degenerative disc disease were randomly assigned to one of the two methods. Researchers measured bone healing, pain, disability, and quality of life one year after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Bone marrow aspirate concentrate (BMAC) with allograft
What this could lead to
If BMAC works as well as traditional bone graft, it could reduce the need for a separate surgical site to harvest bone, potentially lowering pain and recovery time.
What could go wrong
This is a very small, completed study with only 17 participants, so results may not apply to everyone. BMAC is still experimental for this use, and long-term benefits or risks are not fully known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intervertebral disk degenerative disorder lumbar disk degenerative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUMBAR DEGENERATIVE DISC DISEASE

Contacts and locations

Locations

  • Center for Musculoskeletal Care (CMC)

    New York, New York, 10016, United States

  • NY Spine Institute

    Westbury, New York, 11590, United States

  • NYU Hospital for Joint Diseases

    New York, New York, 10003, United States

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