Minimally invasive back surgery may offer same benefits with fewer risks
NCT ID NCT01640977
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared two surgical techniques for treating lumbar degenerative disc disease: traditional open surgery (open PLIF) and a newer, less invasive version (MAS PLIF). Researchers tracked complications and pain relief in 67 adults who needed spinal fusion. The goal was to see if the less invasive approach could offer similar or better results with fewer side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Posterior lumbar interbody fusion (PLIF) surgery, either open or minimally invasive (MAS PLIF)
What this could lead to
If MAS PLIF proves safer or equally effective with fewer complications, it could become a preferred surgical option for patients with lumbar disc disease.
What could go wrong
This is a small, observational study (67 participants) comparing two surgical techniques, not a randomized trial. Results may not apply to all patients, and any surgery carries risks like infection or nerve damage.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Kuether Brain and Spine
Greensboro, North Carolina, 27401, United States
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Nova Neurosurgical Brain and Spine
Greensboro, North Carolina, 27401, United States
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Scott and White Healthcare
Temple, Texas, 76508, United States
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WellSpan Orthopedics-York
York, Pennsylvania, 17405, United States